ARG70060
Human IL17B recombinant protein (Active) (His-tagged, C-ter)
Human IL17B recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Active Human IL17B recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | IL17B |
| 物种 | Human |
| A.A. 序列 | Gln21 - Phe180 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is less than 49 ng/mL. |
| 別名 | IL-17B; Interleukin-20; Interleukin-17B; IL-20; Neuronal interleukin-17-related factor; NIRF; Cytokine Zcyto7; ZCYTO7 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is<0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | IL17B |
|---|---|
| 全名 | interleukin 17B |
| 背景介绍 | The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. [provided by RefSeq, Jul 2008] |
| 生物功能 | Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
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