ARG83299
Human HNMT ELISA Kit
Human HNMT ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG83299 Human HNMT ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human HNMT in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | HNMT |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 15 pg/ml |
| 检测范围 | 62.5 pg/ml - 4,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 4.9% Inter-Assay CV: 4.7% |
| 別名 | HMT; Histamine N-methyltransferase; EC 2.1.1.8; HNMT-S1; HNMT-S2 |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
|---|---|
| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HNMT |
| 全名 | histamine N-methyltransferase |
| 背景介绍 | In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [UniProt] |
| 细胞定位 | Cytoplasm. |
检测图片 (1) Click the Picture to Zoom In
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ARG83299 Human HNMT ELISA Kit standard curve image
ARG83299 Human HNMT ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83299 Human HNMT ELISA Kit User manual |
 Download
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