ARG83298
Human HEXA ELISA Kit
Human HEXA ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG83298 Human HEXA ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human HEXA in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | HEXA |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 75 pg/ml |
| 检测范围 | 312 pg/ml - 20,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 4.6% Inter-Assay CV: 5.0% |
| 別名 | N-acetyl-beta-glucosaminidase subunit alpha; Beta-N-acetylhexosaminidase subunit alpha; EC 3.2.1.52; TSD; Beta-hexosaminidase subunit alpha; Hexosaminidase subunit A |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HEXA |
| 全名 | hexosaminidase A (alpha polypeptide) |
| 背景介绍 | This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq, Jul 2009] |
| 生物功能 | Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity. [UniProt] |
| 翻译后修饰 | N-linked glycan at Asn-115 consists of Man(3)-GlcNAc(2). |
检测图片 (1) Click the Picture to Zoom In
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ARG83298 Human HEXA ELISA Kit standard curve image
ARG83298 Human HEXA ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83298 Human HEXA ELISA Kit User manual |
 Download
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