ARG70390

Human GIF / Gastric intrinsic factor recombinant protein (His-tagged, C-ter)

Human GIF / Gastric intrinsic factor recombinant protein (His-tagged, C-ter) for SDS-PAGE

概述

产品描述 E. coli expressed, His-tagged (C-ter) Human GIF / Gastric intrinsic factor recombinant protein
应用 SDS-PAGE
靶点名称 GIF / Gastric intrinsic factor
物种 Human
A.A. 序列 Met1 - Tyr417
表达系统 E. coli
Protein Full name Cobalamin binding intrinsic factor
別名 CBLIF; Cobalamin Binding Intrinsic Factor; IFMH; INF; IF; TCN3; GIF; Gastric Intrinsic Factor (Vitamin B Synthesis); Gastric Intrinsic Factor; Intrinsic Factor

属性

形式 Powder
纯化说明 Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
纯度 > 98% (by SDS-PAGE)
缓冲液 PBS (pH 8.0)
复溶 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely.
存放说明 For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 CBLIF
全名 Cobalamin Binding Intrinsic Factor
背景介绍 This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia.
生物功能 Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis.
细胞定位 Secreted
翻译后修饰 Disulfide bond, Glycoprotein, Phosphoprotein

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  • ARG70390 Human GIF / Gastric intrinsic factor recombinant protein (His-tagged, C-ter) SDS-PAGE image

    SDS-PAGE analysis of  ARG70390 Human GIF / Gastric intrinsic factor recombinant protein (His-tagged, C-ter)