ARG81997
Human GAS6 ELISA Kit
Human GAS6 ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG81997 Human GAS6 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human GAS6 in serum, plasma and cell culture supernatants. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | No cross-reactivity or interference with the following recombinant Human proteins: ApoAI, BMP1, BMP2, BMP3, BMP4, BMP7, CRP, HGF, HSP27, IL1 alpha, IL1 RI, IL1 beta, IL1RA, IL2, IL4, IL5, IL6, IL8, IL10, IL12, IL13, IL15, IL17C, IL21, IL23, IFN gamma, MMP2, sIL2R, sIL6R, PDGF, PLA2G7, prolactin, TGF beta 1, TGF beta 2, TGF beta 3, TLR1, TLR2, TLR3, TNF alpha, TNF RI, TNF RII and VEGF. |
| 靶点名称 | GAS6 |
| 偶联标记 | HRP |
| 偶联标记说明 | Read at 450 nm. |
| 灵敏度 | 6 pg/ml |
| 样品类型 | Serum, plasma and cell culture supernatants. |
| 标准范围 | 31 - 2000 pg/ml |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: 6% Inter-Assay CV: 9% |
| 別名 | Growth arrest-specific protein 6; AXLLG; AXSF; GAS-6; AXL receptor tyrosine kinase ligand |
应用说明
| 检测时间 | ~ 3 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GAS6 |
| 全名 | growth arrest-specific 6 |
| 背景介绍 | This gene encodes a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia. [provided by RefSeq, Aug 2014] |
| 生物功能 | Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses. [UniProt] |
| 产品亮点 | Related products: GAS6 antibodies; GAS6 ELISA Kits; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | Isoform 1 is proteolytically processed after secretion to yield a N-terminal 36 kDa protein and a C-terminal 50 kDa protein including the laminin G-like domains which activates AXL. Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG81997 Human GAS6 ELISA Kit standard curve image
ARG81997 Human GAS6 ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG81997 Human GAS6 ELISA Kit User manual |
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