ARG83283
Human Factor XI ELISA Kit
Human Factor XI ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG83283 Human Factor XI ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Factor XI in Serum, Plasma and Cell culture supernatants. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | Factor XI |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 25 pg/ml |
| 检测范围 | 0.78 ng/ml - 50 ng/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 4.8% Inter-Assay CV: 5.2% |
| 別名 | F11; Coagulation Factor XI; FXI; Plasma Thromboplastin Antecedent; PTA; Coagualtion Factor XI; EC 3.4.21.27; EC 3.4.21 |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | F11 |
| 全名 | Coagulation Factor XI |
| 背景介绍 | This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. |
| 生物功能 | Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. |
| 细胞定位 | Secreted |
| 翻译后修饰 | Disulfide bond, Glycoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG83283 Human Factor XI ELISA standard curve image
ARG83283 Human Factor XI ELISA results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83283 Human Factor XI ELISA User manual |
 Download
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