ARG83282
Human Factor X ELISA Kit
Human Factor X ELISA 试剂盒 for ELISA and Human
Cell Biology and Cellular Response antibody
概述
产品描述 | ARG83282 Human Factor X ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Factor X in Serum, Plasma and Cell culture supernatants. |
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反应物种 | Hu |
应用 | ELISA |
特异性 | There is no detectable cross-reactivity with other relevant proteins. |
靶点名称 | Factor X |
偶联标记 | HRP |
偶联标记说明 | Substrate: TMB and read at 450 nm. |
灵敏度 | 25 pg/ml |
检测范围 | 0.78 ng/ml - 50 ng/ml |
样品类型 | Serum, Plasma and Cell culture supernatants |
精确 | Intra-Assay CV: 5.2% Inter-Assay CV: 6.0% |
別名 | FX; Stuart factor; EC 3.4.21.6; Stuart-Prower factor; FXA; Coagulation factor X |
应用说明
检测时间 | ~ 5 hours |
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属性
形式 | 96 well |
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存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | F10 |
全名 | coagulation factor X |
背景介绍 | Factor X is the first enzyme in the common pathway of blood coagulation. It can be activated by Factor IXa (with Factor VIII cofactor) of the contact pathway and by Factor VIIa of the tissue factor pathway. After activation, It cleaves prothrombin to form thrombin. Thrombin not only transforms Fibrinogen to form Fibrin and but also activates Factor XIII to stabilize Fibrin in the thrombus. |
生物功能 | Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody |
翻译后修饰 | The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway). The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains. |
检测图片 (1) Click the Picture to Zoom In
Title | Download Link |
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ARG83282 Human Factor X ELISA Kit User manual |
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