ARG83282

Human Factor X ELISA Kit

Human Factor X ELISA 试剂盒 for ELISA and Human

Cell Biology and Cellular Response antibody

概述

产品描述 ARG83282 Human Factor X ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Factor X in Serum, Plasma and Cell culture supernatants.
反应物种 Hu
应用 ELISA
特异性 There is no detectable cross-reactivity with other relevant proteins.
靶点名称 Factor X
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm.
灵敏度 25 pg/ml
检测范围 0.78 ng/ml - 50 ng/ml
样品类型 Serum, Plasma and Cell culture supernatants
精确 Intra-Assay CV: 5.2%
Inter-Assay CV: 6.0%
別名 FX; Stuart factor; EC 3.4.21.6; Stuart-Prower factor; FXA; Coagulation factor X

应用说明

检测时间 ~ 5 hours

属性

形式 96 well
存放说明 Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 2159 Human F10

Swiss-port # P00742 Human Coagulation factor X

基因名称 F10
全名 coagulation factor X
背景介绍 Factor X is the first enzyme in the common pathway of blood coagulation. It can be activated by Factor IXa (with Factor VIII cofactor) of the contact pathway and by Factor VIIa of the tissue factor pathway. After activation, It cleaves prothrombin to form thrombin. Thrombin not only transforms Fibrinogen to form Fibrin and but also activates Factor XIII to stabilize Fibrin in the thrombus.
生物功能 Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. [UniProt]
研究领域 Cell Biology and Cellular Response antibody
翻译后修饰 The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).
The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.

检测图片 (1) Click the Picture to Zoom In

  • ARG83282 Human Factor X ELISA Kit standard curve image

    ARG83282 Human Factor X ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG83282 Human Factor X ELISA Kit User manual download icon Download