ARG81603

Human FOLR2 ELISA Kit

Human FOLR2 ELISA 试剂盒 for ELISA and Human

内含物

货号 内含物名称 包装 温度
ARG81603-001 Antibody-coated microplate 8 X 12 strips 4°C. Unused strips should be sealed tightly in the air-tight pouch.
ARG81603-002 Standard 2 X 10 ng/vial 4°C
ARG81603-003 Standard/Sample diluent 30 ml (Ready to use) 4°C
ARG81603-004 Antibody conjugate concentrate (100X) 1 vial (100 µl) 4°C
ARG81603-005 Antibody diluent buffer 12 ml (Ready to use) 4°C
ARG81603-006 HRP-Streptavidin concentrate (100X) 1 vial (100 µl) 4°C
ARG81603-007 HRP-Streptavidin diluent buffer 12 ml (Ready to use) 4°C
ARG81603-008 25X Wash buffer 20 ml 4°C
ARG81603-009 TMB substrate 10 ml (Ready to use) 4°C (Protect from light)
ARG81603-010 STOP solution 10 ml (Ready to use) 4°C
ARG81603-011 Plate sealer 4 strips Room temperature

概述

产品描述 ARG81603 Human FOLR2 ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human FOLR2 in serum and cell culture supernatants.
反应物种 Hu
应用 ELISA
特异性 There is no detectable cross-reactivity with other relevant proteins.
靶点名称 FOLR2
偶联标记 HRP
偶联标记说明 Substrate: TMB and read at 450 nm.
灵敏度 78 pg/ml
样品类型 Serum and cell culture supernatants.
标准范围 156 - 10000 pg/ml
样本量 100 µl
精确 Intra-Assay CV: 6.0%
Inter-Assay CV: 7.6%
別名 Folate receptor 2; BETA-HFR; FBP; Folate receptor beta; Folate receptor, fetal/placental; FBP/PL-1; FR-beta; FR-P3; Placental folate-binding protein; FR-BETA

应用说明

检测时间 ~ 5 hours

属性

形式 96 well
存放说明 Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 2350 Human FOLR2

Swiss-port # P14207 Human Folate receptor beta

基因名称 FOLR2
全名 folate receptor 2 (fetal)
背景介绍 The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能 Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. [UniProt]
产品亮点 Related products:
FOLR2 antibodies; FOLR2 ELISA Kits;
New ELISA data calculation tool:
Simplify the ELISA analysis by GainData
翻译后修饰 N-glycosylated. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG81603 Human FOLR2 ELISA Kit standard curve image

    ARG81603 Human FOLR2 ELISA Kit results of a typical standard run with optical density reading at 450 nm.

Title Download Link
ARG81603 Human FOLR2 ELISA Kit User's manual download icon Download