ARG70111
Human FGF4 recombinant protein (Active) (His-tagged, C-ter)
Human FGF4 recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-tagged (C-ter) Active Human FGF4 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | FGF4 |
| 物种 | Human |
| A.A. 序列 | Gly25 - Leu206 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is < 2.5 ng/mL. The specific activity of recombinant human FGF-4 is > 4 x 10^5 IU/mg. |
| 別名 | K-FGF; HST-1; FGF-4; Transforming protein KS3; HSTF-1; Heparin secretory-transforming protein 1; Fibroblast growth factor 4; KFGF; HST; Heparin-binding growth factor 4; HBGF-4; HSTF1 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS containing 0.1% sarkosyl (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | FGF4 |
|---|---|
| 全名 | fibroblast growth factor 4 |
| 背景介绍 | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG70111 Human FGF4 recombinant protein (Active) (His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70111 Human FGF4 recombinant protein (Active) (His-tagged, C-ter).
