ARG70128
Human FGF22 recombinant protein (Active) (His-SUMO tagged, N-ter)
Human FGF22 recombinant protein (Active) (His-SUMO tagged, N-ter) for SDS-PAGE
概述
| 产品描述 | E. coli expressed, His-SUMO tagged (N-ter) Active Human FGF22 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | FGF22 |
| 物种 | Human |
| A.A. 序列 | Thr23 - Ser170 |
| 表达系统 | E. coli |
| 生物活性 | Active |
| 活性说明 | Determined by its ability to induce 3T3 cells proliferation. The ED50 for this effect is < 2 ng/mL. |
| 別名 | Fibroblast growth factor 22; FGF-22 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 98% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 8.0) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | FGF22 |
|---|---|
| 全名 | fibroblast growth factor 22 |
| 背景介绍 | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| 生物功能 | Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG70128 Human FGF22 recombinant protein (Active) (His-SUMO tagged, N-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70128 Human FGF22 recombinant protein (Active) (His-SUMO tagged, N-ter).
