ARG82000
Human ELABELA (ELA32, ELA21) ELISA Kit
Human ELABELA (ELA32, ELA21) ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG82000 Human ELABELA (ELA32, ELA21) ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human ELABELA (ELA32, ELA21) in serum and plasma. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Cross Reactivity: ELA32 (Human) and ELA21 (Human, Mouse, Rat): 100% ANP (Mouse, Rat), Adrenomedullin (Human), BNP-32 (Human), CNP22 (Human, Rat, Mouse, Porcine), Apelin 36 (Human), Apelin 12 (Human, Mouse, Rat, Bovine) and Copeptin (Human): 0% |
| 靶点名称 | ELABELA |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.25 ng/ml |
| 检测范围 | Linear range: 0.25 - 2.7 ng/ml |
| 样品类型 | Serum and Plasma |
| 标准范围 | 0.01 - 100 ng/ml |
| 样本量 | 50 µl |
| 精确 | Intra-Assay CV: less than 10%; Inter-Assay CV: less than 15% |
| 別名 | Protein Toddler; tdl; ELA; Protein Elabela; Apelin receptor early endogenous ligand; Ende |
应用说明
| 检测时间 | ~ 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P0DMC3 Human Apelin receptor early endogenous ligand |
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| 基因名称 | APELA |
| 全名 | apelin receptor early endogenous ligand |
| 背景介绍 | This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. [provided by RefSeq, Jul 2016] |
| 生物功能 | Hormone required during early development for endoderm differentiation and heart morphogenesis by acting as a ligand for the apelin receptor (APLNR). Acts as a motogen by promoting endoderm and mesendoderm cell migration during gastrulation by binding and activating the apelin receptor, thereby driving internalization of the apelin receptor. Plays a key role during heart development by acting as a ligand for the apelin receptor (By similarity). [UniProt] |
| 细胞定位 | Secreted. Secreted, extracellular space. Note=Found in blood plasma (PubMed:28137936). Found in serum of pregnant mice, peaking at midgestation; indicating a maternal and zygotic origin of circulating APELA during pregnancy (By similarity). [UniProt] |
| 产品亮点 | Related products: New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
检测图片 (1) Click the Picture to Zoom In
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ARG82000 Human ELABELA (ELA32, ELA21) ELISA Kit standard curve image
ARG82000 Human ELABELA (ELA32, ELA21) ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG82000 Human ELABELA (ELA32, ELA21) ELISA Kit User manual |
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