ARG83261
Human Cathepsin C ELISA Kit
Human Cathepsin C ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG83261 Human Cathepsin C ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Cathepsin C in Serum, Plasma and Cell culture supernatants. |
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| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | There is no detectable cross-reactivity with other relevant proteins. |
| 靶点名称 | Cathepsin C |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 100 pg/ml |
| 检测范围 | 156 pg/ml - 10,000 pg/ml |
| 样品类型 | Serum, Plasma and Cell culture supernatants |
| 精确 | Intra-Assay CV: 5.5% Inter-Assay CV: 4.3% |
| 別名 | CTSC; Cathepsin C; Dipeptidyl Peptidase 1; DPP1; Dipeptidyl Transferase; Cathepsin J; EC 3.4.14.1; DPP-I; CPPI; DPPI; PALS; PLS; Dipeptidyl-Peptidase I; Dipeptidyl Peptidase I; PDON1; HMS; JPD; JP |
应用说明
| 检测时间 | ~ 5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CTSC |
| 全名 | Cathepsin C |
| 背景介绍 | This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. |
| 生物功能 | Activates serine proteases such as elastase, cathepsin G and granzymes A and B. |
| 细胞定位 | Lysosome |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Zymogen |
检测图片 (1) Click the Picture to Zoom In
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ARG83261 Human Cathepsin C ELISA Kit standard curve image
ARG83261 Human Cathepsin C ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83261 Human Cathepsin C ELISA Kit User manual |
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