ARG70299
Human CD273 / PD-L2 recombinant protein (Fc-His-tagged, C-ter)
Human CD273 / PD-L2 recombinant protein (Fc-His-tagged, C-ter) for Binding Activity,SDS-PAGE and Human
概述
| 产品描述 | HEK293 expressed, Fc-His-tagged (C-ter) Human CD273 / PD-L2 recombinant protein. |
|---|---|
| 反应物种 | Hu |
| 应用 | Binding, SDS-PAGE |
| 靶点名称 | CD273 / PD-L2 |
| 物种 | Human |
| A.A. 序列 | Leu20 - Pro219 of Human CD273 / PD - L2 (NP_079515.2) with an Fc - 6X His tag at the C - terminus. |
| 表达系统 | HEK293 |
| 別名 | B7DC; bA574F11.2; PDL2; CD antigen CD273; PD-L2; Programmed cell death 1 ligand 2; CD273; Btdc; PDCD1L2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; PD-1 ligand 2; PDCD1 ligand 2 |
应用说明
| 应用说明 | Binding activity test: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human PD-1 at 5µg/ml (100 µl/well) can bind Recombinant Human PD-L2 with a linear range of 0.06-0.24µg/ml. |
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属性
| 形式 | Powder |
|---|---|
| 纯化说明 | 0.22 µm filter sterilized. Endotoxin level is <0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | Reconstitute to a concentration of 0.1 - 0.5 mg/ml in sterile distilled water. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | PDCD1LG2 |
|---|---|
| 全名 | programmed cell death 1 ligand 2 |
| 生物功能 | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). [UniProt] |
| 细胞定位 | Isoform 3: Secreted. Isoform 2: Endomembrane system; Single-pass type I membrane protein. Isoform 1: Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 31 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG70299 Human CD273 / PD-L2 recombinant protein (ECD) (Fc-His-tagged, C-ter) SDS-PAGE image
SDS-PAGE analysis of ARG70299 Human CD273 / PD-L2 recombinant protein (ECD) (Fc-His-tagged, C-ter).
