ARG70527
Human CD22 recombinant protein (His-tagged)
Human CD22 recombinant protein (His-tagged) for SDS-PAGE
概述
| 产品描述 | HEK293 expressed, His-tagged Human CD22 recombinant protein |
|---|---|
| 应用 | SDS-PAGE |
| 靶点名称 | CD22 |
| 物种 | Human |
| A.A. 序列 | Asp 20 - Arg 687 |
| 表达系统 | HEK293 |
| 別名 | CD22; CD22 Molecule; SIGLEC2; CD22 Antigen; SIGLEC-2; Sialic Acid-Binding Ig-Like Lectin 2; B-Lymphocyte Cell Adhesion Molecule; T-Cell Surface Antigen Leu-14; B-Cell Receptor CD22; BL-CAM; Sialic Acid Binding Ig-Like Lectin 2; Siglec-2 |
属性
| 形式 | Powder |
|---|---|
| 纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | PBS (pH 7.4) |
| 复溶 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
| 存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CD22 |
|---|---|
| 全名 | CD22 Molecule |
| 背景介绍 | Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. Implicated in diffuse large B-cell lymphoma. [provided by Alliance of Genome Resources, Nov 2024] |
| 生物功能 | If this negative signaling from is of sufficient strength, apoptosis of the B-cell can be induced. [Uniprot] |
