ARG82245
Human BNP ELISA Kit
Human BNP ELISA 试剂盒 for ELISA and Human
概述
| 产品描述 | ARG82245 Human BNP ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human BNP in serum and plasma. (Peptide extraction is recommended) |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 特异性 | Cross-Reactivity: BNP-32 (Human): 100% BNP-32 (Rat): <0.04% BNP-45 (Rat), BNP-26 (Pig), alpha ANP (1-28) (Human, Dog), Endothelin-1 (Human, Rat, Pig, Mouse, Dog, Bovine), Angiotensin II (Human) and VIP (Human, Rat, Pig): 0% |
| 靶点名称 | BNP |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.26 ng/ml |
| 样品类型 | Serum and plasma. (Peptide extraction is recommended) |
| 标准范围 | 0.01 - 100 ng/ml |
| 样本量 | 50 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 15% |
| 別名 | 4-27; Natriuretic peptides B; 1-28; 1-29; 5-32; BNP; 1-32; 1-30; BNP-32; 5-29; 2-31; 4-30; 4-31; 4-32; 3-29; Gamma-brain natriuretic peptide; 3-30; 5-31; 3-32; 4-29 |
应用说明
| 检测时间 | 4 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NPPB |
| 全名 | natriuretic peptide B |
| 背景介绍 | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014] |
| 生物功能 | Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 产品亮点 | Related products: BNP antibodies; BNP ELISA Kits; BNP Duos / Panels; New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| 翻译后修饰 | The brain natriuretic peptide 32 form is cleaved at Pro-104 by the prolyl endopeptidase FAP (seprase) activity (in vitro). [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG82245 Human BNP ELISA Kit standard curve image
ARG82245 Human BNP ELISA Kit results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG82245 Human BNP ELISA Kit User manual |
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