ARG70093
Human BMP8a recombinant protein (Active) (His-tagged, C-ter)
Human BMP8a recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
概述
产品描述 | E. coli expressed, His-tagged (C-ter) Active Human BMP8a recombinant protein |
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应用 | SDS-PAGE |
靶点名称 | BMP8a |
物种 | Human |
A.A. 序列 | Ala264 - His402 |
表达系统 | E. coli |
生物活性 | Active |
活性说明 | Determined by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is 10-19.4 ng/mL. |
別名 | BMP-8A; Bone morphogenetic protein 8A |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
纯度 | > 98% (by SDS-PAGE) |
缓冲液 | 20 mM sodium citrate and 0.2 M NaCl (pH 3.5) |
复溶 | It is recommended to reconstitute the lyophilized protein in 4 mM HCl to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | BMP8A |
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全名 | bone morphogenetic protein 8a |
生物功能 | Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT. [UniProt] |
细胞定位 | Secreted. [UniProt] |
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