ARG70088
Human BMP3 recombinant protein (Active) (His-tagged, C-ter)
Human BMP3 recombinant protein (Active) (His-tagged, C-ter) for SDS-PAGE
概述
产品描述 | E. coli expressed, His-tagged (C-ter) Active Human BMP3 recombinant protein |
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应用 | SDS-PAGE |
靶点名称 | BMP3 |
物种 | Human |
A.A. 序列 | Gln363 - Arg472 |
表达系统 | E. coli |
生物活性 | Active |
活性说明 | Determined by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is < 10 μg/mL. |
別名 | BMP-3; Bone morphogenetic protein 3; Osteogenin; BMP-3A; Bone morphogenetic protein 3A |
属性
形式 | Powder |
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纯化说明 | Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test. |
纯度 | > 95% (by SDS-PAGE) |
缓冲液 | 20 mM sodium citrate and 0.2 M NaCl (pH 3.5) |
复溶 | It is recommended to reconstitute the lyophilized protein in 4 mM HCl to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min at room temperature to make sure the protein is dissolved completely. |
存放说明 | For long term, lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C or -80°C for up to one month. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | BMP3 |
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全名 | bone morphogenetic protein 3 |
背景介绍 | BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. [provided by RefSeq, Jul 2008] |
生物功能 | Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. [UniProt] |
细胞定位 | Secreted. [UniProt] |
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