ARG83484
Hamster beta 2 Microglobulin ELISA Kit
Hamster beta 2 Microglobulin ELISA 试剂盒 for ELISA and Hamster
概述
| 产品描述 | ARG83484 Hamster beta 2 Microglobulin ELISA Kit is an Enzyme Immunoassay kit for the quantification of Hamster beta 2 Microglobulin in Tissue culture media |
|---|---|
| 反应物种 | Hm |
| 应用 | ELISA |
| 靶点名称 | beta 2 Microglobulin |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.15 ng/mL |
| 样品类型 | Tissue culture media |
| 标准范围 | 0.3125 - 20 ng/mL |
| 样本量 | 100 µl |
| 精确 | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| 別名 | B2M; Beta-2-Microglobulin; Beta Chain Of MHC Class I Molecules; Beta-2-Microglobin; IMD43 |
应用说明
| 检测时间 | 3 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | B2M |
|---|---|
| 全名 | beta-2-microglobulin |
| 背景介绍 | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. |
| 生物功能 | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation. |
| 细胞定位 | Amyloid, MHC I, Secreted |
| 翻译后修饰 | Disulfide bond, Glycation, Glycoprotein, Pyrrolidone carboxylic acid |
