ARG83744
Glucagon ELISA Kit
Glucagon ELISA 试剂盒 for ELISA and Bovine,Dog,Human,Mouse,Pig,Rat
概述
| 产品描述 | ARG83744 Glucagon ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human, Rat, Mouse, Pig, Bovine, Dog Glucagon in serum and plasma. |
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| 反应物种 | Hu, Ms, Rat, Bov, Dog, Pig |
| 应用 | ELISA |
| 特异性 | Cross Reactivity: Glucagon 100% Oxyntomodulin 100% Not Cross Reactivity: Glucagon-Like Peptide-1 (GLP-1) 0% Glucagon-Like Peptide-2 (GLP-2) 0% Insulin 0% Somatostatin 0% Amylin 0% CGRP 0% Amylin 0% PPP 0% Pro-Insulin 0% |
| 靶点名称 | Glucagon |
| 偶联标记 | HRP |
| 偶联标记说明 | Substrate: TMB and read at 450 nm. |
| 灵敏度 | 0.16 ng/ml |
| 样品类型 | Serum and Plasma |
| 标准范围 | 0.16 - 3.74 ng/ml |
| 样本量 | 50 μl |
| 精确 | Intra-Assay CV: <10% Inter-Assay CV: <15% |
| 別名 | GCG; Glucagon; GLP-1; GLP1; GLP2; GRPP; Glicentin-Related Polypeptide; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Preproglucagon; Pro-Glucagon |
应用说明
| 检测时间 | 4.5 hours |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GCG |
| 全名 | Glucagon |
| 背景介绍 | The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. [Uniprot] |
| 细胞定位 | Secreted. [Uniprot] |
| 翻译后修饰 | Amidation, Cleavage on pair of basic residues, Phosphoprotein. [Uniprot] |
