ARG83407
Caspase 3 Assay Kit
Caspase 3 Assay 试剂盒 for Functional study and Other
概述
| 产品描述 | ARG83407 Caspase 3 Assay Kit can be used to measure Caspase 3 in tissue extracts, cell lysate and other biological fluids. |
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| 反应物种 | Other |
| 应用 | FuncSt |
| 靶点名称 | Caspase 3 |
| 偶联标记说明 | Read at 405 nm |
| 灵敏度 | 3 μmol/ml |
| 样品类型 | Tissue extracts, cell lysate and other biological fluids. |
| 标准范围 | 5 μmol/ml - 500 μmol/ml |
| 样本量 | 40 μl |
| 別名 | CPP-32; Caspase-3; EC 3.4.22.56; Apopain; CASP-3; CPP32; Cysteine protease CPP32; SCA-1; SREBP cleavage activity 1; CPP32B; Protein Yama |
应用说明
| 检测时间 | 1 hour |
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属性
| 形式 | 96 well |
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| 存放说明 | Store the kit at 4°C and -20°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | CASP3 |
|---|---|
| 全名 | caspase 3, apoptosis-related cysteine peptidase |
| 背景介绍 | Caspase-3 is a caspase protein that interacts with caspase-8 and caspase-9. It is encoded by the CASP3 gene. CASP3 orthologs have been identified in numerous mammals for which complete genome data are available. Unique orthologs are also present in birds, lizards, lissamphibians, and teleosts. The CASP3 protein is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6 and 7; and the protein itself is processed and activated by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein |
| Title | Download Link |
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| ARG83407 Caspase 3 Assay Kit User manual |
 Download
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