ARG82127
ACHE Activity Assay Kit (Colorimetric)
ACHE Activity Assay 试剂盒 (Colorimetric) for Functional study and Human,Mouse,Rat,All
概述
| 产品描述 | ARG82127 ACHE Activity Assay Kit (Colorimetric) can be used to measure ACHE activity in serum, plasma and blood. |
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| 反应物种 | Hu, Ms, Rat, All |
| 应用 | FuncSt |
| 靶点名称 | ACHE |
| 偶联标记说明 | Read at 412 nm |
| 灵敏度 | 10 U/L |
| 检测范围 | 10 - 600 U/L |
| 样品类型 | serum, plasma and blood |
| 样本量 | 10 µl |
| 別名 | ARACHE; Acetylcholinesterase; ACEE; EC 3.1.1.7; AChE; N-ACHE; YT |
应用说明
| 应用说明 | Please note that this kit does not include a microplate. |
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| 检测时间 | 10 min |
属性
| 形式 | Liquid |
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| 存放说明 | Store the kit at 2-8°C. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | ACHE |
| 全名 | acetylcholinesterase (Yt blood group) |
| 背景介绍 | Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. [provided by RefSeq, Jul 2008] |
| 生物功能 | Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. [UniProt] |
| 细胞定位 | Cell junction, synapse. Secreted. Cell membrane; Peripheral membrane protein. Isoform T: Nucleus. Note=Only observed in apoptotic nuclei. Isoform H: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG82127 Acetylcholinesterase Activity Assay Kit (Colorimetric) enzyme kinetics graph
Kinetics of 0 or 1000 U/L Acetylcholinesterase reaction, using ARG82127 Acetylcholinesterase Activity Assay Kit (Colorimetric).
| Title | Download Link |
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| ARG82127 Acetylcholinesterase Activity Assay Kit (Colorimetric) User's manual |
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