ARG54059

anti-IkB alpha antibody (N-term)

anti-IkB alpha antibody (N-term) for Western blot and Human,Mouse,Rat

Cancer antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody
publication_link 参考文献2

概述

产品描述 Mouse Monoclonal antibody recognizes NFKBIA
反应物种 Hu, Ms, Rat
应用 WB
宿主 Mouse
克隆 Monoclonal
靶点名称 IkB alpha
抗原物种 Human
抗原 Purified recombinant human IkB-alpha(N-terminus) protein fragments expressed in E.coli.
偶联标记 Un-conjugated

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量 36 kDa

属性

形式 Liquid
纯化 Affinity purified
缓冲液 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol
抗菌剂 0.2% Sodium azide
稳定剂 50% Glycerol
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

基因名称 NFKBIA
背景介绍 Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription
细胞定位 Cytoplasm. Nucleus
产品亮点 Related Antibody Duos and Panels:
ARG30037 Phospho IKB alpha Antibody Duo (Total, pS32/36)
ARG30205 NFkB Activation Antibody Panel
Related products:
IkB alpha antibodies; IkB alpha Duos / Panels;
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研究领域 Cancer antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody

检测图片 (1) Click the Picture to Zoom In

  • ARG54059 anti-IkB alpha antibody (N-term) WB image

    Western blot: 3T3 cell lysate stained with ARG54059 anti-IkB alpha antibody (N-term) at 1:500 dilution.

文献引用

Downregulation of lncRNA NEAT1 alleviates sepsis-induced acute kidney injury

WB / Human

Yuhua Zhou et al.
Central European Journal of Immunology,  (2022)

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Effects and mechanisms of PSS-loaded nanoparticles on coronary microcirculation dysfunction in streptozotocin-induced diabetic cardiomyopathy rats.

WB / Rat

Mao Yongjun et al.
Biomed Pharmacother.,  (2019)

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