ARG54059
anti-IkB alpha antibody (N-term)
anti-IkB alpha antibody (N-term) for Western blot and Human,Mouse,Rat
Cancer antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody
参考文献2
概述
| 产品描述 | Mouse Monoclonal antibody recognizes NFKBIA |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 靶点名称 | IkB alpha |
| 抗原物种 | Human |
| 抗原 | Purified recombinant human IkB-alpha(N-terminus) protein fragments expressed in E.coli. |
| 偶联标记 | Un-conjugated |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 实际分子量 | 36 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.1M Tris-Glycine (pH 7.4), 150 mM NaCl, 0.2% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.2% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | NFKBIA |
|---|---|
| 背景介绍 | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to tranlocate to the nucleus and activate transcription |
| 细胞定位 | Cytoplasm. Nucleus |
| 产品亮点 | Related Antibody Duos and Panels: ARG30037 Phospho IKB alpha Antibody Duo (Total, pS32/36) ARG30205 NFkB Activation Antibody Panel Related products: IkB alpha antibodies; IkB alpha Duos / Panels; Related news: Treatment of Obesity with Celastrol Tumor microenvironments are shown to affect progression of several cancer subtypes Immune signaling protein TLR4 has opposing roles in breast cancer development |
| 研究领域 | Cancer antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody |
检测图片 (1) Click the Picture to Zoom In
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ARG54059 anti-IkB alpha antibody (N-term) WB image
Western blot: 3T3 cell lysate stained with ARG54059 anti-IkB alpha antibody (N-term) at 1:500 dilution.
文献引用
Downregulation of lncRNA NEAT1 alleviates sepsis-induced acute kidney injury
WB / Human
Effects and mechanisms of PSS-loaded nanoparticles on coronary microcirculation dysfunction in streptozotocin-induced diabetic cardiomyopathy rats.
WB / Rat
