ARG30037
Phospho IKB alpha Antibody Duo (Total, pS32/36)
Cancer antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody

内含物
货号 | 内含物名称 | 宿主克隆性 | 反应 | 应用 | 包装 |
---|---|---|---|---|---|
ARG51651 | anti-IKB alpha phospho (Ser32 / Ser36) antibody | Rabbit pAb | Hu, Ms, Rat | ICC/IF, IHC-P, WB | 50 μl |
ARG54059 | anti-IkB alpha antibody (N-term) | Mouse mAb | Hu, Ms, Rat | WB | 50 μl |
概述
产品描述 | IκB-α inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, triggers IκB-α phosphorylated at Ser32/36 and promotes IκB-α ubiquitination and degradation, enabling the dimeric NFkB to translocate to the nucleus and activate transcription. ARG30037 IκB-α phospho Duos (Total, pS32/36), includes an antibody reacts total IκB-α protein and an antibody recognizes IκB-α only when Ser32/36 of IκB-α is phosphorylated. This antibody Duos could be used in evaluation of total or Ser32/36 phosphorylated IκB-α protein in IκB-α/NFkB signaling and IκB-α/NFkB regulation studies. |
---|---|
靶点名称 | IKB alpha |
別名 | Phospho IKB alpha antibody; Phospho nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor alpha antibody; IKB alpha phospho (Ser32 / Ser36) antibody; IkB alpha antibody (N-term) |
属性
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
---|---|
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
全名 | Phospho nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IKB alpha) Antibody Duo (Total, pS32/36) |
---|---|
研究领域 | Cancer antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody |
检测图片 (4) Click the Picture to Zoom In
-
ARG51651 anti-IKB alpha phospho (Ser32/Ser36) antibody WB image
Western Blot: extracts from HeLa cells untreated or treated with TNF stained with anti-I kappa B alpha (phospho Ser32/Ser36) antibody ARG51651.
-
ARG51651 anti-IKB alpha phospho (Ser32/Ser36) antibody IHC-P image
Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-I kappa B alpha (phospho Ser32/Ser36) antibody ARG51651 (left) or the same antibody preincubated with blocking peptide (right).
-
ARG51651 anti-IKB alpha phospho (Ser32/Ser36) antibody ICC/IF image
Immunofluorescence: methanol-fixed HeLa cells stained with anti-I kappa B alpha (phospho Ser32/Ser36) antibody ARG51651.
-
ARG54059 anti-IkB alpha antibody (N-term) WB image
Western blot: 3T3 cell lysate stained with ARG54059 anti-IkB alpha antibody (N-term) at 1:500 dilution.