ARG30037

Phospho IKB alpha Antibody Duo (Total, pS32/36)

Datasheet

参考文献2

订购信息

包装

价格

1 pair

5,626

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产品说明书
参考文献 (2)

内含物

货号	内含物名称	宿主克隆性	反应	应用	包装
ARG51651	anti-IKB alpha phospho (Ser32 / Ser36) antibody	Rabbit pAb	Hu, Ms, Rat	ICC/IF, IHC-P, WB	50 μl
ARG54059	anti-IkB alpha antibody (N-term)	Mouse mAb	Hu, Ms, Rat	WB	50 μl

概述

产品描述	IκB-α inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, triggers IκB-α phosphorylated at Ser32/36 and promotes IκB-α ubiquitination and degradation, enabling the dimeric NFkB to translocate to the nucleus and activate transcription. ARG30037 IκB-α phospho Duos (Total, pS32/36), includes an antibody reacts total IκB-α protein and an antibody recognizes IκB-α only when Ser32/36 of IκB-α is phosphorylated. This antibody Duos could be used in evaluation of total or Ser32/36 phosphorylated IκB-α protein in IκB-α/NFkB signaling and IκB-α/NFkB regulation studies.
靶点名称	IKB alpha
別名	Phospho IKB alpha antibody; Phospho nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor alpha antibody; IKB alpha phospho (Ser32 / Ser36) antibody; IkB alpha antibody (N-term)

产品描述

IκB-α inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, triggers IκB-α phosphorylated at Ser32/36 and promotes IκB-α ubiquitination and degradation, enabling the dimeric NFkB to translocate to the nucleus and activate transcription.

ARG30037 IκB-α phospho Duos (Total, pS32/36), includes an antibody reacts total IκB-α protein and an antibody recognizes IκB-α only when Ser32/36 of IκB-α is phosphorylated. This antibody Duos could be used in evaluation of total or Ser32/36 phosphorylated IκB-α protein in IκB-α/NFkB signaling and IκB-α/NFkB regulation studies.

靶点名称

IKB alpha

別名

Phospho IKB alpha antibody; Phospho nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor alpha antibody; IKB alpha phospho (Ser32 / Ser36) antibody; IkB alpha antibody (N-term)

属性

存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

全名	Phospho nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IKB alpha) Antibody Duo (Total, pS32/36)
研究领域	Cancer antibody; Gene Regulation antibody; Immune System antibody; Signaling Transduction antibody

检测图片 (4) Click the Picture to Zoom In

ARG51651 anti-IKB alpha phospho (Ser32/Ser36) antibody WB image

Western Blot: extracts from HeLa cells untreated or treated with TNF stained with anti-I kappa B alpha (phospho Ser32/Ser36) antibody ARG51651.
ARG51651 anti-IKB alpha phospho (Ser32/Ser36) antibody IHC-P image

Immunohistochemistry: paraffin-embedded human breast carcinoma tissue stained with anti-I kappa B alpha (phospho Ser32/Ser36) antibody ARG51651 (left) or the same antibody preincubated with blocking peptide (right).
ARG51651 anti-IKB alpha phospho (Ser32/Ser36) antibody ICC/IF image

Immunofluorescence: methanol-fixed HeLa cells stained with anti-I kappa B alpha (phospho Ser32/Ser36) antibody ARG51651.
ARG54059 anti-IkB alpha antibody (N-term) WB image

Western blot: 3T3 cell lysate stained with ARG54059 anti-IkB alpha antibody (N-term) at 1:500 dilution.