ARG67045
anti-ROR gamma antibody [SQab30332]
anti-ROR gamma antibody [SQab30332] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant rabbit Monoclonal antibody [SQab30332] recognizes ROR gamma |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30332 |
| 同位型 | IgG |
| 靶点名称 | ROR gamma |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human ROR gamma |
| 偶联标记 | Un-conjugated |
| Protein Full name | Nuclear receptor ROR-gamma |
| 別名 | RORC, RAR Related Orphan Receptor C, NR1F3, RZRG, RORG, TOR, Nuclear Receptor Subfamily 1 Group F Member 3, RAR-Related Orphan Receptor C, Nuclear Receptor ROR-Gamma, Nuclear Receptor RZR-Gamma, Retinoid-Related Orphan Receptor Gamma, Retinoid-Related Orphan Receptor-Gamma, Retinoic Acid-Binding Receptor Gamma, RZR-GAMMA, IMD42 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0). Incubate the samples at RT (18-25°C) for 44 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Tonsil |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05%BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05%BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | RORC |
|---|---|
| 全名 | RAR Related Orphan Receptor C |
| 背景介绍 | The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 生物功能 | Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of cellular differentiation, immunity, peripheral circadian rhythm as well as lipid, steroid, xenobiotics and glucose metabolism. [UniProt] |
| 细胞定位 | Nucleus |
| 预测分子量 | 58 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG67045 anti-ROR gamma antibody [SQab30332] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded tonsil stained with ARG67045 anti-ROR gamma antibody [SQab30332].
