anti-PPAR alpha antibody

anti-PPAR alpha antibody for Flow cytometry,ICC/IF,Immunohistochemistry,Western blot and Human,Mouse,Rat

Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody
publication_link 参考文献3


产品描述 Mouse Monoclonal antibody recognizes PPAR alpha
反应物种 Hu, Ms, Rat
宿主 Mouse
克隆 Monoclonal
同位型 IgG1, kappa
靶点名称 PPAR alpha
抗原物种 Human
抗原 Recombination protein of Human PPAR alpha (Swiss: Q07869).
偶联标记 Un-conjugated
別名 hPPAR; NR1C1; Peroxisome proliferator-activated receptor alpha; PPAR; Nuclear receptor subfamily 1 group C member 1; PPAR-alpha; PPARalpha


应用 推荐稀释比
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.


形式 Liquid
纯化 Purification with Protein G.
缓冲液 PBS and 0.09% (W/V) Sodium azide
抗菌剂 0.09% (W/V) Sodium azide
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.



GeneID: 19013 Mouse PPARA

GeneID: 25747 Rat PPARA

GeneID: 5465 Human PPARA

基因名称 PPARA
全名 peroxisome proliferator-activated receptor alpha
背景介绍 Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
生物功能 Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2. [UniProt]
细胞定位 Nucleus.
研究领域 Cancer antibody; Cell Biology and Cellular Response antibody; Gene Regulation antibody; Metabolism antibody
预测分子量 52 kDa

检测图片 (3) Click the Picture to Zoom In

  • ARG55240 anti-PPAR alpha antibody WB image

    Western blot: 30 μg of HepG2, HEK293T, HCT116, NIH-3T3, Mouse brain, Rat brain and Rat ovary lysates stained with ARG55240 anti-PPAR alpha antibody at 1:500 dilution.

  • ARG55240 anti-PPAR alpha antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG55240 anti-PPAR alpha antibody (green) at 1:25 dilution. Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).

  • ARG55240 anti-PPAR alpha antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human kidney tissue stained with ARG55240 anti-PPAR alpha antibody at 1:25 dilution.


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ICC/IF / Mouse

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WB / Mouse

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Vaccine Against PCSK9 Improved Renal Fibrosis by Regulating Fatty Acid β-Oxidation.

WB / Mouse

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