ARG70286

Human CD48 recombinant protein (ECD) (His-tagged, C-ter)

Human CD48 recombinant protein (ECD) (His-tagged, C-ter) for SDS-PAGE,Binding Activity and Human

概述

产品描述 HEK293 expressed, His-tagged (C-ter) Human CD48 recombinant protein (ECD).
反应物种 Hu
应用 Binding, SDS-PAGE
靶点名称 CD48 (ECD)
物种 Human
A.A. 序列 Gln27 - Ser220 of Human CD48 (NP_001769.2) with 6X His tag at the C-terminus.
表达系统 HEK293
別名 Leukocyte antigen MEM-102; B-lymphocyte activation marker BLAST-1; CD48 antigen; BCM1 surface antigen; CD antigen CD48; TCT.1; BLAST1; BCM1; MEM-102; mCD48; Signaling lymphocytic activation molecule 2; BLAST; hCD48; SLAMF2; SLAM family member 2

应用说明

应用说明 Binding activity test: Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD48 at 5 ug/ml (100 µl/well) can bind recombinant human CD244 with a linear range of 0.2-1 ug/ml.

属性

形式 Powder
纯化说明 0.22 µm filter sterilized. Endotoxin level is less than 0.1 EU/µg of the protein, as determined by the LAL test.
纯度 > 95% (by SDS-PAGE)
缓冲液 PBS (pH 7.4)
重建 Reconstitute to a concentration of 0.1 - 0.5 mg/ml in sterile distilled water.
存放说明 Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 962 Human CD48

Swiss-port # P09326 Human CD48 antigen

基因名称 CD48
全名 CD48 molecule
背景介绍 This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
生物功能 Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. [UniProt]
细胞定位 Cell membrane; Lipid-anchor, GPI-anchor. [UniProt]
预测分子量 28 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG70286 Human CD48 recombinant protein (ECD) (His-tagged, C-ter) SDS-PAGE image

    SDS-PAGE analysis of ARG70286 Human CD48 recombinant protein (ECD) (His-tagged, C-ter).